One of the treatments for Restless Genital Syndrome is…. benzos

Re: Vibrating Genitals?!?!?
« Reply #24 on: November 15, 2017, 04:58:24 pm »

[Buddie]

Quote from: [Buddie] on November 15, 2017, 04:04:14 pm
At this point in my pathetic existence this symptom would be the most exciting thing thats happened to me in 2 years…siiiiiigh
:laugh: :laugh: :laugh:   Okay I’m laughing but when my Vag went westward it was freaky!! :D

Love […] xxx  :smitten: :smitten: :smitten:

Re: Vibrating Genitals?!?!?
« Reply #25 on: November 15, 2017, 11:26:39 pm »

[Buddie]

I wonder if this is withdrawal because I’ve had all kinds of weird sensations down there since I’ve been off Xanax ct for almost 15 months already.

2015: Mass hysteria causes Restless Genital Syndrome outbreak at Benzo Buddies

Cult superstar Perseverance called to account for fear-mongering

PERSEVERANCE: WHAT EXACTLY ARE YOU TRYING TO ACCOMPLISH IN YOUR POSTS?
« on: July 15, 2016, 02:05:25 pm »

[Buddie]

Assuming these posts aren’t a cut & paste patchwork of various research data obtained from the many resources that exist in cyberspace, I do admire you and appreciate the time and painstaking analysis involved in contributing to the BB.org information collective…

…unfortunately, I find the essence of many posts to be discouraging, disheartening, and offering little to no hope to those severely debilitated and crippled from the hellacious symptomatology of iatrogenic illness, as it exists in benzodiazepine withdrawal.

Words such as “permanent;” “irreversible;” and “learning deficit,” inspire hopelessness, fear, and a deep-seated sense of despair and anguish that isn’t easily resolved or relinquished; in fact, often thrusting the reader into a downward spiral, deeper into the abyss.

The scholarly, didactic verbiage that is necessary and inseparable from professional clinical trial and research writing format, further confuses and exacerbates the reader’s fragile psychological state.

For example:
“In rats given benzodiazepines chronically, the common α 1 γ2 sub-units are down-regulated, while rarer sub-units are elevated proportionately (Holt et al, 1999). It is suggested that transcription of the Gene cluster on Chromosome 5 (which encodes for α1 β2 γ2 sub-units) is inhibited on chronic benzodiazepine administration, while the transcription of the Gene cluster on Chromosome 15 is upregulated (Holt et al, 1999). In certain brain regions, the Chromosome-5-encoded receptor sub-unit proteins are replaced by those encoded in Chromosome 15, which show less sensitivity.” (4)

This excerpt is quite esoteric in nature and would require the highest level of comprehension and routine familiarity found mostly in researchers with PhD’s (not practitioners).

The one thing I’ve learned in neurology is that few things are conclusive or certain. BWS is severely under-researched and much is not fully understood by the medical community.

One question I continually ask myself since joining BB.org is, “How many people have I inadvertently hurt through bad advice?”

If for every 500 I helped, but hurt 1, I would cease to interact any further, simply because it’s not my call to make in weighing human wellness, health, and life.

Mad in America attempts to link long-term benzodiazepine use to cancer… except… there is no link

Mad in America

Is Long-term Use of Benzodiazepines a Risk for Cancer?

A large study of the population in Taiwan reveals that long-term use of benzodiazepine drugs, commonly prescribed for anxiety, significantly increases the risk for brain, colorectal, and lung cancers.

http://www.madinamerica.com/2016/03/is-long-term-use-of-benzodiazepine-a-risk-for-cancer/

Original study

Is Long-term Use of Benzodiazepine a Risk for Cancer?

The study strength is that it is a population-based design to evaluate the risk for cancers. However, this study also have some limitations regarding data information like alcoholism, smoking status and lifestyle which is not available in the BNHI database and could influence on the findings. Another limitation could be related to cohort study design regarding population sample and confounding adjustments, even after adjustments there could be unknown confounders which might create bias to results. The inclusion of non-users which might not be pure controls as we studied the cancer risk between users and nonusers. Another limitation could be the simplified e-claim by general physicians in Taiwan. It is always lower quality then the randomized control trial studies as BNHI data serves for administrative billing not for scientific validation purpose. Moreover, the number of drug uses are just for reference which might not provide accurate reflection whether the individuals taken drugs as recommended by practitioners. In Taiwan, the NHI reimburse for maximum 90 days prescription as well as the self-pay category was not included in this study. Since, in this study we observed BZDs exposure but not their mechanism and metabolism related to cancer which could be also limitation. Therefore, further animal or cellular model are needed to help in identifying a possible biological mechanism linking BZDs with risk of cancers.

http://journals.lww.com/md-journal/Fulltext/2015/02020/Is_Long_term_Use_of_Benzodiazepine_a_Risk_for.7.aspx?WT.mc_id=EMxALLx20100222xxFRIEND